The response of prion genic variation to selection for scrapie resistance in Hungarian indigenous sheep breeds
نویسندگان
چکیده
منابع مشابه
Breeding for resistance to scrapie: Detection of polymorphisms in the prion protein gene in German sheep breeds
Scrapie is a fatal neurodegenerative disease of sheep and goats belonging to the group of transmissible spongiform encephalopathies (TSE). TSEs are characterised by distinctive pathology, the involvement of a hostencoded prion protein (PrP) in disease development and genetic control of susceptibility. Polymorphisms in three different codons of the ovine prion protein (PrP) gene (136, 154, 171) ...
متن کاملIntraspecies Prion Transmission Results in Selection of Sheep Scrapie Strains
BACKGROUND Sheep scrapie is caused by multiple prion strains, which have been classified on the basis of their biological characteristics in inbred mice. The heterogeneity of natural scrapie prions in individual sheep and in sheep flocks has not been clearly defined. METHODOLOGY/PRINCIPAL FINDINGS In this study, we intravenously injected 2 sheep (Suffolk and Corriedale) with material from a n...
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انتخاب نامساعد یکی از مشکلات اساسی در صنعت بیمه است. که ابتدا در سال 1960، توسط روتشیلد واستیگلیتز مورد بحث ومطالعه قرار گرفت ازآن موقع تاکنون بسیاری از پژوهشگران مدل های مختلفی را برای تجزیه و تحلیل تقاضا برای صنعت بیمه عمر که تماما ناشی از عدم قطعیت در این صنعت میباشد انجام داده اند .وهدف از آن پیدا کردن شرایطی است که تحت آن شرایط انتخاب یا کنار گذاشتن یک بیمه گزار به نفع و یا زیان شرکت بیمه ...
15 صفحه اولQuantifying diversity losses due to selection for scrapie resistance in three endangered Spanish sheep breeds using microsatellite information.
The effect of selection for scrapie resistance on genetic variability in three endangered Spanish sheep breeds (Colmenareña, Mallorquina and Rubia de El Molar) was studied using two different criteria for quantifying contributions to genetic variability: (a) molecular coancestry or genetic identity; and (b) average number of alleles per locus or allelic richness. A total of 236 (81 Colmenareña,...
متن کاملPrion protein (PrP) gene polymorphisms and breeding for resistance to scrapie in Polish Merino sheep
Genetic susceptibility or resistance of sheep to scrapie is associated with polymorphisms particularly in the three codons 136, 154 and 171 of the ovine prion protein (PrP) gene. The aim of the study was to reveal the PrP haplotype and genotype distribution in the Polish Merino breed and to make a forecast of the application of a scrapie resistance breeding programme for this breed. PCR-RFLP an...
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ژورنال
عنوان ژورنال: Acta Veterinaria Hungarica
سال: 2018
ISSN: 0236-6290,1588-2705
DOI: 10.1556/004.2018.050